Lianfa Shi Selected Research

trimethylaminocarboxyldihydroboran (TCDB)

1/2018	Cysteine Protease-Mediated Autocleavage of Clostridium difficile Toxins Regulates Their Proinflammatory Activity.
10/2016	Intravenous adenovirus expressing a multi-specific, single-domain antibody neutralizing TcdA and TcdB protects mice from Clostridium difficile infection.
4/2015	Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells.
2/2015	Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.
9/2014	A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice.
1/2014	Utility of Clostridium difficile toxin B for inducing anti-tumor immunity.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Lianfa Shi Research Topics

Disease

3	Diarrhea 10/2016 - 08/2012
3	Clostridium Infections 10/2016 - 08/2012
2	Inflammation (Inflammations) 01/2018 - 08/2012
2	Infections 01/2018 - 01/2015
2	Colitis 10/2016 - 02/2015
2	Neoplasms (Cancer) 01/2014 - 05/2005
1	Pseudomembranous Enterocolitis (Pseudomembranous Colitis) 04/2015
1	Toxemia 01/2015
1	Melanoma (Melanoma, Malignant) 01/2014
1	Colorectal Neoplasms (Colorectal Cancer) 01/2014

Drug/Important Bio-Agent (IBA)

6	trimethylaminocarboxyldihydroboran (TCDB)IBA 01/2018 - 01/2014
3	Anti-Bacterial Agents (Antibiotics)IBA 10/2016 - 08/2012
2	Virulence Factors (Pathogenicity Factors)IBA 01/2018 - 02/2015
2	Single-Domain AntibodiesIBA 10/2016 - 09/2014
1	Clostridium difficile tcdA proteinIBA 01/2018
1	ExotoxinsIBA 04/2015
1	AntibodiesIBA 01/2015
1	Neutralizing AntibodiesIBA 01/2015
1	Clostridium difficile toxB proteinIBA 01/2014
1	Immunotoxins (Immunotoxin)IBA 08/2012
1	VaccinesIBA 08/2012
1	Granzymes (Granzyme)IBA 05/2005
1	PerforinIBA 05/2005

Therapy/Procedure

1	Therapeutics 01/2018